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Thread: ChemoTherapy Regimen For Ca

  1. #1
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    Post ChemoTherapy Regimen For Ca

    Anal Cancer


    Concurrent chemoradiation for localized cancer

    5-FU + Mitomycin + RT regimen 1
    5-FU 1000 mg/m2/d civi d1-4 and 29-32
    Mitomycin 10 mg/m2 iv bolus d1 and 29
    Concurrent radiotherapy 1.8 Gy/d x 5/w for 5 weeks to 45 Gy
    4-6 weeks later, perform full thickness biopsy. If biopsy positive for residual tumor, start salvage treatment:
    5-FU 1000 mg/m2/d civi d1-4
    Cisplatin (CDDP) 100 mg/m2 iv over 4-6 hrs d2
    Concurrent radiotherapy 1.8 Gy/d x 5 to 9 Gy
    6 weeks later, perform another full thickness biopsy. If still positive, do abdominoperineal resection

    5-FU + Mitomycin + RT regimen 2
    5-FU 200 mg/m2/d civi d1-26
    Mitomycin 10 mg/m2 iv d1
    Concurrent radiotherapy to 36 Gy over 4 wks
    2 wks later
    5-FU 200 mg/m2/d civi d1-17
    Mitomycin 10 mg/m2 iv d1
    Concurrent radiotherapy to 23.4 Gy over 17 days




    Chemotherapy for metastatic cancer

    5-FU + Cisplatin
    5-FU 1000 mg/m2/d civi d1-5
    Cisplatin (CDDP) 100 mg/m2 iv d2
    Q4w

  2. #2
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    Biliary Tract Cancer



    Gemcitabine
    Gemcitabine (Gemzar) 1000 mg/m2 iv d1, 8
    Q3w


    Docetaxel
    Docetaxel (Taxotere) 100 mg/m2 iv
    Q3w

    Gemcitabine + Capecitabine
    Gemcitabine (Gemzar) 1000 mg/m2 iv d1, 8
    Capecitabine (Xeloda) 650 mg/m2/d po bid d1-14
    Q3w


    Gemcitabine + Cisplatin
    Gemcitabine (Gemzar) 1250 mg/m2 iv d1, 8
    Cisplatin (CDDP) 75 mg/m2 iv d1
    Q3w


    Gemcitabine + Oxaliplatin
    Gemcitabine (Gemzar) 1000 mg/m2 iv d1
    Oxaliplatin (Eloxatin) 100 mg/m2 iv d2
    Q2w


    5-FU + Cisplatin
    5-FU 1000 mg/m2/d civi d1-5
    Cisplatin (CDDP) 100 mg/m2 iv d2
    Q3w


    LV5FU-P
    Leucovorin 200 mg/m2 iv over 2 hrs d1
    5-FU 400 mg/m2 iv bolus, followed by 600 mg/m2 iv over 22 hrs, d1 and 2
    Cisplatin (CDDP) 50 mg/m2 iv d2
    Q2w


    Erlotinib
    Erlotinib (Tarceva) 150 mg po qd

  3. #3
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    Bladder Cancer


    Neoadjuvant chemotherapy for stage II, III and non-metastatic stage IV cancer


    MVAC
    Methotrexate (MTX) 30 mg/m2 iv d1, 15 and 22
    Vinblastine 3 mg/m2 iv d1, 15 and 22
    Doxorubicin (Adriamycin) 30 mg/m2 iv d2
    Cisplatin (CDDP) 70 mg/m2 iv d2
    Q4w x 3 cycles



    Concurrent chemoradiation for stage II, III and non-metastatic stage IV cancer

    Cisplatin + RT
    Cisplatin (CDDP) 100 mg/m2 iv d1 and 22
    Concurrent radiotherapy to 39.6 Gy
    Followed by consolidation
    Cisplatin (CDDP) 100 mg/m2 iv d1
    Radiotherapy to 25.2 Gy



    Chemotherapy for metastatic cancer

    MVAC
    Methotrexate (MTX) 30 mg/m2 iv d1, 15 and 22
    Vinblastine 3 mg/m2 iv d1, 15 and 22
    Doxorubicin (Adriamycin) 30 mg/m2 iv d2
    Cisplatin (CDDP) 70 mg/m2 iv d2
    Q4w x 6 cycles



    Gemcitabine + Cisplatin
    Gemcitabine (Gemzar) 1000 mg/m2 iv over 30-60 min d1, 8 and 15
    Cisplatin (CDDP) 70 mg/m2 iv d2
    Q4w x 6 cycles



    Carboplatin + Paclitaxel
    Carboplatin (Paraplatin) AUC 6 iv d1
    Paclitaxel (Taxol) 225 mg/m2 iv over 3 hrs d1
    Q3w x 6 cycles


    Gemcitabine + Paclitaxel
    Gemcitabine (Gemzar) 1000 mg/m2 iv d1, 8 and 15
    Paclitaxel (Taxol) 200 mg/m2 iv over 3 hrs d1
    Q3w x 6 cycles


    Gemcitabine + Cisplatin + Paclitaxel
    Gemcitabine (Gemzar) 1000 mg/m2 iv over 30-60 min d1, 8
    Cisplatin (CDDP) 70 mg/m2 iv d1
    Paclitaxel (Taxol) 80 mg/m2 iv d1, 8
    Q3w x 6 cycles


    Pemetrexed
    Pemetrexed (Alimta) 500 mg/m2 iv over 10 min q3w untill disease progression

    Start vitamin supplements 1 week before initial dose of pemetrexed:
    Folic acid 350-1000 mcg/day orally till 21 days after last dose of pemetrexed.
    Vitamin B12 1000 mcg I.M. every 9 weeks.
    Dexamethasone 4 mg twice daily the day before, the day of and the day after pemetrexed

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    Breast Cancer



    Adjuvant therapy



    Hormonal therapy

    Tamoxifen
    Tamoxifen 20 mg po qd x 5 years

    Tamoxifen + Goserelin
    Tamoxifen 20 mg po qd
    Goserelin (Zoladex) 3.6 mg sc qm

    LHRH-agonists in Early Breast Cancer Overview Group. Use of luteinising-hormone-releasing hormone agonists as adjuvant treatment in premenopausal patients with hormone-receptor-positive breast cancer: a meta-analysis of individual patient data from randomised adjuvant trials. Lancet 2007; 369:1711 (link to the article).

    Anastrozole
    Anastrozole (Arimidex) 1 mg po qd x 5 years or x 3 years after 2 years of tamoxifen


    Letrozole
    Letrozole (Femara) 2.5 mg po qd x 5 years


    Exemestane
    Exemestane (Aromasin) 25 mg po qd x 2-3 years after 3-2 years of tamoxifen or 5 years after 5 years of tamoxifen




    Chemotherapy

    AC
    Doxorubicin (Adriamycin) 60 mg/m2 iv d1
    Cyclophosphamide ((Cytoxan) 600 mg/m2 iv d1
    Q3w x 4 cycles


    TC
    Docetaxel (Taxotere) 75 mg/m2 iv over 30-60 min d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv over 30-60 min d1
    Q3w x 4 cycles


    CMF PO
    Cyclophosphamide (Cytoxan) 100 mg/m2/d po d1-14
    Methotrexate (MTX) 40 mg/m2 iv d1 and 8
    5-FU 600 mg/m2 iv d1 and 8
    Q4w x 6 cycles


    CMF IV
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv d1
    Methotrexate (MTX) 40 mg/m2 iv d1
    5-FU 600 mg/m2 iv d1
    Q3w x 6 cycles


    Epirubicin→CMF
    Epirubicin 100 mg/m2 iv q3w x 4 cycles
    Followed by CMF x 4 cycles

    CAF
    Regimen 1 po
    Cyclophosphamide (Cytoxan) 100 mg/m2/d po d1-14
    Doxorubicin (Adriamycin) 30 mg/m2 iv d1, 8
    5-FU 500 mg/m2 iv d1, 8
    Q4w x 6 cycles


    Regimen 2 iv
    Cyclophosphamide (Cytoxan) 500 mg/m2 iv d1
    Doxorubicin (Adriamycin) 50 mg/m2 iv d1
    5-FU 500 mg/m2 iv d1
    Q3w x 6 cycles


    AC→Paclitaxel Q3w
    Doxorubicin (Adriamycin) 60 mg/m2 iv push over 5-15 min d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv over 30-60 min d1
    Q3w x 4 cycles
    Followed by
    Paclitaxel (Taxol) 175 mg/m2 iv over 3 hours
    Q3w x 4 cycles


    AC→Paclitaxel Qw
    Doxorubicin (Adriamycin) 60 mg/m2 iv push over 5-15 min d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv over 30-60 min d1
    Q3w x 4 cycles
    Followed by
    Paclitaxel (Taxol) 80 mg/m2 iv over 1 hour
    Qw x 12 cycles


    AC→Docetaxel Q3w
    Doxorubicin (Adriamycin) 60 mg/m2 iv push over 5-15 min d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv over 30-60 min d1
    Q3w x 4 cycles
    Followed by
    Docetaxel (Taxotere) 100 mg/m2 iv over 1 hour
    Q3w x 4 cycles


    AC→Docetaxel Qw
    Doxorubicin (Adriamycin) 60 mg/m2 iv push over 5-15 min d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv over 30-60 min d1
    Q3w x 4 cycles
    Followed by
    Docetaxel (Taxotere) 35 mg/m2 iv over 1 hour
    Qw x 12 cycles


    AT→T
    Doxorubicin (Adriamycin) 50 mg/m2 iv d1
    Paclitaxel (Taxol) 200 mg/m2 iv d1
    Q3w x 4 cycles
    Followed by
    Paclitaxel (Taxol) 80 mg/m2 iv over 1 h qw x 12 weeks


    Dose-dense AC→T
    Doxorubicin (Adriamycin) 60 mg/m2 iv d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv d1
    Q2w x 4 cycles
    Followed by
    Paclitaxel (Taxol) 175 mg/m2 iv
    Q2w x 4 cycles
    Filgrastim (Neupogen) or pegfilgrastim (Neulasta) support


    TAC
    Docetaxel (Taxotere) 75 mg/m2 iv d1
    Doxorubicin (Adriamycin) 50 mg/m2 iv d1
    Cyclophosphamide (Cytoxan) 500 mg/m2 iv d1
    Q3w x 6 cycles
    Filgrastim (Neupogen) support


    EFC→D
    Epirubicin 100 mg/m2 iv d1
    5-FU 500 mg/m2 iv d1
    Cyclophosphamide (Cytoxan) 500 mg/m2 iv d1
    Q3w x 3 cycles
    Followed by
    Docetaxel (Taxotere) 100 mg/m2 iv
    Q3w x 3 cycles

    CEF
    Cyclophosphamide (Cytoxan) 75 mg/m2 po qd d1-14
    Epirubicin 60 mg/m2 iv d1 and 8
    5-FU 500 mg/m2 iv d1 and 8
    Q4w x 6 cycles

    Dose-dense EC→T
    Epirubicin 120 mg/m2 iv d1
    Cyclophosphamide (Cytoxan) 830 mg/m2 iv d1
    Q2w x 6 cycles
    Paclitaxel (Taxol) 175 mg/m2 iv
    Q3w x 4 cycles
    Filgrastim (Neupogen) 5 mcg/kg sc d2-13
    Epoetin alfa (Procrit) 40,000 units sc qw

    Dose-dense Epirubicin→Paclitaxel→Cyclophosphamide
    Epirubicin 150 mg/m2
    Q2w x 3 cycles
    Paclitaxel (Taxol) 225 mg/m2
    Q2w x 3 cycles
    Cyclophosphamide (Cytoxan) 2500 mg/m2
    Q2w x 3 cycles
    Filgrastim (Neupogen) 5 mcg/kg sc d 3-10


    MFL
    Methotrexate (MTX) 100 mg/m2 iv d1, 8
    5-FU 600 mg/m2 iv d1, 8
    Leucovorin 15 mg/m2 po q6h x 6 doses beginning 24 hrs after methotrexate
    Q4w x 6 cycles





    Targeted therapy

    AC→TH
    Doxorubicin (Adriamycin) 60 mg/m2 iv d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv d1
    Q3w x 4 cycles
    Followed by
    Paclitaxel (Taxol) 175 mg/m2 iv q3w x 4 cycles, or 80 mg/m2 iv qw x 12 weeks
    Trastuzumab (Herceptin) 4 mg/kg loading dose beginning with paclitaxel, then 2 mg/kg iv qw x 1 year


    Dose-dense AC→TH
    Doxorubicin (Adriamycin) 60 mg/m2 iv d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv d1
    Q2w x 4 cycles
    Followed by
    Paclitaxel (Taxol) 175 mg/m2 iv q2w x 4 cycles, and
    Trastuzumab (Herceptin) 4 mg/kg loading dose beginning with the first cycle of paclitaxel, then 2 mg/kg iv qw during paclitaxel treatment, followed by 6 mg/kg iv q3w, for a total of 1 year
    Pegfilgrastim (Neulasta) 6 mg sc d2

    TCH
    Docetaxel (Taxotere) 75 mg/m2 iv d1 q3w x 6 cycles
    Carboplatin (Paraplatin) AUC 6 iv d1 q3w x 6 cycles
    Trastuzumab (Herceptin) 4 mg/kg loading dose followed by 2 mg/kg iv qw during chemotherapy; then 6 mg/kg iv q3w,for a total of 1 year


    Chemo→H
    Trastuzumab (Herceptin) can be given after completion of chemotherapy as well, loading dose 8 mg/kg,followed by 6 mg/kg,iv q3w for a total of 1 year.


    DH→FEC
    Docetaxel (Taxotere) 100 mg/m2 iv over 1 h d1 q3w x 3 cycles
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min d1 and then 2 mg/kg iv over 30 min qw x 8 (total of 9 treatments)
    Followed by
    5-FU 600 mg/m2 iv d1
    Epirubicin 60 mg/m2 iv d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv d1
    Q3w x 3 cycles






    Metastatic breast cancer



    Hormonal therapy


    Tamoxifen
    Tamoxifen 20 mg po qd


    Anastrozole
    Anastrozole (Arimidex) 1 mg po qd


    Anastrozole + Goserelin
    Goserelin (Zoladex) 3.6 mg sc d1 qm
    Anastrozole (Arimidex) 1 mg po qd, beginning on d22


    Letrozole
    Letrozole (Femara) 2.5 mg po qd


    Exemestane
    Exemestane (Aromasin) 25 mg po qd


    Fulvestrant
    Fulvestrant (Faslodex) 250 mg im qm or 500 mg loading dose im d1 followed by 250 mg im d14, 28 and qm thereafter




    Chemotherapy

    Docetaxel
    Docetaxel (Taxotere)
    Regimen 1 (q3w)
    60-100 mg/m2 iv q3w


    Regimen 2 (qw)
    35-40 mg/m2 iv qw x 6 wks every 8 wks


    Paclitaxel
    Paclitaxel (Taxol)
    Regimen 1 (q3w)
    175 mg/m2 iv over 3 hours q3w until progression or limiting toxicity


    Regimen 2 (qw)
    80-90 mg/m2 iv over 1 hour qw until progression or limiting toxicity


    Abraxane
    Abraxane
    Regimen 1 (qw)
    100 mg/m2 or 150 mg/m2 iv qw x 3 weeks every 4 weeks


    Regimen 2 (q3w)
    260 mg/m2 iv q3w


    Gemcitabine
    Gemcitabine (Gemzar) 725 mg/m2 iv qw x 3 wks evey 4wks

    Carmichael, J et al. Advanced breast cancer: a phase II trial with gemcitabine. J Clin Oncol 1995; 13:2731 (link to the article).

    Vinorelbine
    Vinorelbine (Navelbine) 30 mg/m2 iv qw


    Capecitabine
    Capecitabine (Xeloda) 1250 mg/m2 po bid x 14 days q3w


    AC
    Doxorubicin (Adriamycin) 60 mg/m2 iv
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv
    Q3w

    EC
    Epirubicin 75 mg/m2 iv d1
    Cyclophosphamide (Cytoxan) 600 mg/m2 iv d1
    Q3w


    EP
    Epirubicin 75 mg/m2 iv d1
    Paclitaxel (Taxol) 200 mg/m2 iv over 3 hours d1
    Q3w


    Docetaxel + Capecitabine
    Docetaxel (Taxotere) 75 mg/m2 iv d1
    Capecitabine (Xeloda) 1000 mg/m2 po bid x 14 days
    Q3w


    Paclitaxel + Gemcitabine
    Paclitaxel (Taxol) 175 mg/m2 iv d1
    Gemcitabine (Gemzar) 1000 mg/m2 iv d1 and 8
    Q3w


    Ixabepilone (Ixempra)
    Ixabepilone (Ixempra)
    Premedication
    Diphenhydramine (Benadrol) 50 mg po 1 hour before ixabepilone
    Ranitidine (Zantac) 150 mg po 1 hour before ixabepilone
    If allergic reaction, add dexamethasone 20 mg po 1 hour before ixabepilone or 20 mg iv 30 min before ixabepilone

    Regimen 1
    40 mg/m2 iv over 3 hours q3w

    Regimen 2
    6 mg/m2/d iv d1-5 q3w


    Ixabepilone + Capecitabine
    Ixabepilone (Ixempra) 40 mg/m2 iv over 3 hours d1
    Capecitabine (Xeloda) 1000 mg/m2 po bid d1-14
    Q3w until progression




    Targeted therapy

    Paclitaxel + Bevacizumab
    Paclitaxel (Taxol) 90 mg/m2 iv d1, 8 and 15
    Bevacizumab (Avastin) 10 mg/kg iv d1 and 15
    Q4w


    Capecitabine + Bevacizumab
    Capecitabine (Xeloda) 1000-1250 mg/m2 po bid d1-14
    Bevacizumab (Avastin) 15 mg/kg iv d1
    Q3w until disease progression


    Trastuzumab
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min first wk followed by 2 mg/kg iv over 30 min qw


    Trastuzumab + Anastrozole (for postmenopausal women with Her2 and ER/PR + cancer)
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min first wk followed by 2 mg/kg iv over 30 min qw
    Anastrozole (Arimidex) 1 mg po qd

    Trastuzumab + Paclitaxel q3w
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min first wk followed by 2 mg/kg iv over 30 min qw
    Paclitaxel (Taxol) 175 mg/m2 iv q3w


    Trastuzumab + Paclitaxel qw
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min first wk followed by 2 mg/kg iv over 30 min qw
    Paclitaxel (Taxol) 90 mg/m2 iv qw


    Trastuzumab + Docetaxel (TH) q3w
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min first wk followed by 2 mg/kg iv over 30 min qw (may change to 6 mg/kg q3w after chemotherapy) until disease progression
    Docetaxel (Taxotere) 100 mg/m2 iv q3w x 6-8 cycles


    Trastuzumab + Docetaxel qw
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min first wk followed by 2 mg/kg iv over 30 min qw
    Docetaxel (Taxotere) 35 mg/m2 iv qw


    TCH
    Docetaxel (Taxotere) 75 mg/m2 iv over 1 h d1 q3w x 6-8 cycles
    Carboplatin (Paraplatin) AUC 6 iv over 1 h d1 q3w x 6-8 cycles
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min first week followed by 2 mg/kg iv over 30 min qw (may change to 6 mg/kg q3w after chemotherapy) until disease progression


    Trastuzumab + Capecitabine
    Regimen 1
    Trastuzumab (Herceptin) 4 mg/kg iv over 90 min first week followed by 2 mg/kg iv over 30 min qw
    Capecitabine (Xeloda) 1250 mg/m2 po bid d1-14 q3w


    Regimen 2
    Trastuzumab (Herceptin) 8 mg/kg iv loading dose followed by 6 mg/kg iv q3w
    Capecitabine (Xeloda) 1250 mg/m2 po bid d1-14 q3w


    Trastuzumab + Docetaxel + Capecitabine
    Trastuzumab (Herceptin) 8 mg/kg iv loading followed by 6 mg/kg iv d1 q3w
    Docetaxel (Taxotere) 75 mg/m2 iv d1 q3w
    Capecitabine (Xeloda) 940 mg/m2 po bid d1-14 q3w


    Lapatinib + Capecitabine
    Lapatinib (Tykerb) 1250 mg po qd
    Capecitabine (Xeloda) 1000 mg/m2 po bid d1-14 q3w

    Lapatinib + Paclitaxel
    Lapatinib (Tykerb) 1500 mg po qd
    Paclitaxel (Taxol) 175 mg/m2 iv q3w


    Lapatinib (for inflammatory breast cancer)
    Lapatinib (Tykerb) 1500 mg po qd


    Lapatinib (for brain metastases)
    Lapatinib (Tykerb) 750 mg po bid


    Lapatinib + Capecitabine (for brain metastases)
    Lapatinib (Tykerb) 1250 mg po qd
    Capecitabine (Xeloda) 1000 mg/m2 po bid x 14 days q3w

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    Cancer of Unknown Primary



    Gemcitabine + Carbplatin + Paclitaxel→ Paclitaxel
    Gemcitabine (Gemzar) 1000 mg/m2 iv d1, 8
    Carbplatin (Paraplatin) AUC 5 iv d1
    Paclitaxel (Taxol) 200 mg/m2 iv d1
    Q3w x 4 cycles
    Followed by
    Paclitaxel (Taxol) 70 mg/m2 iv qw x 6 wks every 8 wks x 3 cycles


    Carboplatin + Paclitaxel + Etoposide
    Carboplatin (Paraplatin) AUC 6 iv d1
    Paclitaxel (Taxol) 200 mg/m2 iv d1
    Etoposide (VP-16) 50 mg alternating with 100 mg po d1-10
    Q3w


    Cisplatin + Etoposide + Bleomycin
    Cisplatin (CDDP) 20 mg/m2/d iv d1-5
    Etoposide (VP-16) 100 mg/m2/d iv d1-5
    Bleomycin 30 U iv d1, 8 and 15
    Q3w


    Bevacizumab + Erlotinib
    Bevacizumab (Avastin) 10 mg/kg iv over 30-90 min q2w
    Erlotinib (Tarceva) 150 mg po qd

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    Carcinoid Tumor



    Octreotide 150-250 mcg sc tid or depot 20 mg im q4w


    Streptozocin + 5-FU
    Streptozocin 500 mg/m2/d iv d1-5
    5-FU 400 mg/m2/d iv d1-5
    Q6w

    Streptozocin + Doxorubicin
    Streptozocin 500 mg/m2/d iv d1-5
    Doxorubicin (Adriamycin) 50 mg/m2 iv d1, 22


    Etoposide + Cisplatin
    Etoposide (VP-16) 130 mg/m2/d civi d1-3
    Cisplatin (CDDP) 45 mg/m2/d civi d2-3
    Q3w

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    Cervical Cancer


    Concurrent chemoradiation

    Cisplatin + RT
    Cisplatin (CDDP) 40 mg/m2 iv qw
    Concurrent radiotherapy 55-75 Gy

    Cisplatin + 5-FU + RT
    Cisplatin (CDDP) 70 mg/m2 iv d1 q3w x 2 cycles
    5-FU 1000 mg/m2/d civi d1-4 q3w x 2 cycles
    Concurrent radiotherapy 49.3 Gy
    Followed by
    Cisplatin (CDDP) 70 mg/m2 iv d1 q3w x 2 more cycles
    5-FU 1000 mg/m2/d civi d1-4 q3w x 2 more cycles


    Neoadjuvant chemotherapy

    Cisplatin + Paclitaxel
    Cisplatin (CDDP) 60 mg/m2 iv d1
    Paclitaxel (Taxol) 60 mg/m2 iv d1
    Every 10 days x 3 cycles



    Chemotherapy for stage IVB (metastatic) cancer

    Cisplatin
    Cisplatin (CDDP) 50 mg/m2 iv
    Q3w


    Paclitaxel
    Paclitaxel (Taxol) 110-200 mg/m2 iv
    Q3w


    Vinorelbine
    Vinorelbine (Navelbine) 30 mg/m2 iv
    Qw


    Topotecan
    Topotecan (Hycamtin) 1.5 mg/m2/d iv d1-5
    Q3-4w



    Cisplatin + Topotecan
    Cisplatin (CDDP) 50 mg/m2 iv d1
    Topotecan (Hycamtin) 0.75 mg/m2/d iv d1-3
    Q3w x 6 cycles



    Cisplatin + Paclitaxel
    Cisplatin (CDDP) 50 mg/m2 iv d1
    Paclitaxel (Taxol) 135 mg/m2 iv d1
    Q3w


    Carboplatin + Docetaxel
    Carboplatin (Paraplatin) AUC 6 iv d1
    Docetaxel (Taxotere) 60 mg/m2 iv d1
    Q3w

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    Myelodysplastic Syndrome


    Azacitidine
    Azacitidine (Vidaza)
    75 mg/m2/d sc qd x 7 days q4w


    Decitabine (Dacogen)
    Regimen 1
    20 mg/m2/d iv over 1 h d1-5 q4w


    Regimen 2
    15 mg/m2 iv over 3 hrs q8h x 3 days q6w


    Lenalidomide
    Lenalidomide (Revlimid)
    10 mg po qd


    Imatinib (for MDS/MPD associated with PDGFR gene re-arrangements)
    Imatinib (Gleevec) 400 mg po qd


    Antithymocyte globulin (ATG)
    40 mg/kg/d iv d1-4


    Cyclosporine
    Cyclosporine 5-6 mg/kg/d po bid, adjust for blood levels between 100 to 300 ng/mL

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    Does Anyone remember all doses?


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    Talking

    Quote Originally Posted by vitrag24 View Post
    Does Anyone remember all doses?
    If someone can then i'll call him god.....

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