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Thread: question about renal function

  1. #1
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    Default question about renal function

    can someone tell me the difference between acute/chronic renal failure versus acute/chronic renal insufficiency versus azotemia?

  2. #2
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    Renal Failure


    Kidney Functions:
    • Remove toxic waste products
    • Remove excess water and salts
    • Play a part in controlling blood pressure
    • Produce erythropoetin (epo) which stimulates red cell production
    • Helps to keep calcium and phosphate in balance for healthy bones
    • Maintains proper pH for the blood


    Terms:
    • Azotemia: Elevated blood urea nitrogen
      (BUN>28mg/dL) & Creatinine (Cr>1.5mg/dL)
    • Uremia: azotemia with symptoms or signs of renal failure
    • End Stage Renal Disease (ESRD): uremia requiring transplantation or dialysis
    • Chronic Renal Failure (CRF): irreversible kidney dysfunction with azotemia >3 mos.
    • Creatinine Clearance (CCr): rate of filtration of creatinine by the kidney (marker for GFR)
    • Glomerular Filtration Rate (GFR): the total rate of filtration of blood by the kidney.


    Acute Renal Failure:
    • Prerenal azotemia
      An abnormally high level of nitrogen-type wastes in the bloodstream. It is caused by conditions that reduce blood flow to the kidneys.
    • Postrenal azotemia
      An obstruction of some kind (i.e., bladder cancer, uric acid crystals, urethral stricture etc)
    • Intrinsic Renal Disease
      Usually glomerular disease
      Usually leads to End Stage Renal Disease


    Stages of Chronic Renal Failure:
    • Silent – GFR up to 50 ml/min.
    • Renal insufficiency – GFR 25 to 50 ml/min.
    • Renal failure – GFR 5 to 25 ml/min
    • End-stage renal failure – GFR less than 5 ml/min.


    Uremic Syndrome:
    Uremia occurs in stage 3 & 4 of CRF. It means literally “urine in the blood”
    • Symptomatic azotemia
    • Fever, Malaise
    • Anorexia, Nausea
    • Mild neural dysfunction
    • Uremic pruritus (itching)
    for reading!

  3. #3
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    Thumbs up gooood!!

    Very nice presentation..Thanx 4 making it this easily "readable"
    O you who believe! Seek help in patience and As-Salât (the prayer). Truly! Allâh is with As-Sâbirin (the patient ones). (Al-Baqarah 2:153)

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    nice
    thnx

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