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Thread: biochemistry mnemonics

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    Cool biochemistry mnemonics

    Essential amino acids
    PVT. TIM HALL:
    Phe
    Val
    Thr
    Trp
    Ile
    Met
    His
    Arg
    Leu
    Lys
    Pvt. is short for Private in the military.
    Arg and His are considered semiessential.
    Alternatively: "MATT VIL PHLy".
    Dicarboxylic acids (alpha, omega) C2 through C10: common names
    "Oh My, Such Good Apple Pie, Sweet As Sugar!":
    Oxalic
    Malonic
    Succinic
    Glutaric
    Adipic
    Pimelic
    Suberic
    Azelaic
    Sebacic
    Vitamins: which are fat soluble
    KADE:
    Vitamin K
    Vitamin A
    Vitamin D
    Vitamin E
    Na/K pump: concentrations of Na vs. K on inside/outside of cell, pump action, number of molecules moved
    HIKIN':
    There is a HIgh K concentration INside the cell.
    From this can deduce that the Na/K pump pumps K into cell and Na out of cell.
    Alternatively: When I was learning this pump (circa 1992), a band that was "in" was Kris Kross, and a band that was "out" was "Sha Na Na Na":
    So pump moves K K (2 K) in and Na Na Na (3 Na) out.
    Sadly, as infectious as their debut album was, Kris Kross can really no longer be classed as "in".

    Glycolysis steps
    "Goodness Gracious, Father Franklin Did Go By Picking Pumpkins (to) Prepare Pies":
    Glucose
    Glucose-6-P
    Fructose-6-P
    Fructose-1,6-diP
    Dihydroxyacetone-P
    Glyceraldehyde-P
    1,3-Biphosphoglycerate
    3-Phosphoglycerate
    2-Phosphoglycerate (to)
    Phosphoenolpyruvate [PEP]
    Pyruvate
    'Did', 'By' and 'Pies' tell you the first part of those three: di-, bi-, and py-.
    'PrEPare' tells location of PEP in the process.
    Citric acid cycle compounds
    "Oh Citric Acid Is Of (course) A SiLly STupid Funny Molecule":
    Oxaloacetate
    Citrate
    Aconitate
    Isocitrate
    Oxalosuccinate
    Alpha-ketoglutarate
    SuccinyL-CoA
    SuccinaTe
    Fumarate
    Malate
    SilLy and sTupid used to differentiate succinyL and succinaTe
    B vitamin names
    "The Rhythm Nearly Proved Contagious":
    In increasing order:
    Thiamine (B1)
    Riboflavin (B2)
    Niacin (B3)
    Pyridoxine (B6)
    Cobalamin (B12)
    AcetylCoA and acetacetylCoA: amino acids forming them
    "A Lighter Lease" (A LyTr LeIs):
    A=AcetylCoA or Acetoacetyl CoA
    Ly=Lysine
    Tr=Tryptophan
    Le=Leucine
    Is=Isoleucine
    Fabry's disease
    FABRY'S:
    Foam cells found in glomeruli and tubules/ Febrile episodes
    Alpha galactosidase A deficiency/ Angiokeratomas
    Burning pain in extremities/ BUN increased in serum/ Boys
    Renal failure
    YX genotype (male, X linked recessive)
    Sphingolipidoses
    Citric acid cycle compounds
    "Can I Keep Selling Sex For Money, Officer?":
    Citrate
    Isocitrate
    alpha Ketogluterate
    Succinyl CoA
    Succinate
    Fumerate
    Malate
    Oxaloacetate

    Hypervitaminosis A: signs and symptoms
    "Increased Vitamin A makes you HARD":
    Headache/ Hepatomegaly
    Anorexia/ Alopecia
    Really painful bones
    Dry skin/ Drowsiness

    Golgi complex: functions
    "Golgi Distributes A SPAM":
    Distributes proteins and lipids from ER
    Add mannose onto specific lysosome proteins
    Sulfation of sugars and slected tyrosine
    Proteoglycan assembly
    Add O-oligosugars to serine and threnonine
    Modify N-ologosugars on aspara

    Citric acid cycle compounds
    "Oh! Can I Keep Some Succinate For Myself?":
    Oxaloacetate
    Citrate
    Isocitrate
    Ketoglutarate
    Succinyl coA
    Succinate
    Fumarate
    Malate
    G protein type for respective receptors
    "KISS and KICK till you're SICK of SEX" (QISS and QIQ till you're SIQ of SQS):
    This gives the G-protein type (Gq, Gi, or Gs) for all the receptors. Receptors are in alphabetical order:
    alpha1=Q
    alpha2=I
    beta1=S
    beta3=S
    M1=Q
    M2=I
    M3=Q
    D1=S
    D2=I
    H1=Q
    H2=S
    V1=Q
    V2=S
    Folate deficiency: causes
    A FOLIC DROP:
    Alcoholism
    Folic acid antagonists
    Oral contraceptives
    Low dietary intake
    Infection with Giardia
    Celiac sprue
    Dilatin
    Relative folate deficiency
    Old
    Pregnant

    Metabolic acidosis (normal anion-gap): causes
    With hyperkalemia: RAISE K+:
    RTA type 4
    Aldosterone or mineralocorticord deficiency
    Iatrogenic: NH4Cl, HCl
    "Stenosis": obstructive uropathy
    Early uremia
    With hypokalemia: ReDUCE K+:
    Renal TA type 1 and 2
    Diarrhoea
    Urine diversion into gut
    Carbonate anhydrase inhibitor
    Ex-hyperventilation
    this song is awesome
    Amino acids: properties
    Sung to the Beverly Hillbillies melody
    :

    Come an' listen to my story about the a-mi-nos
    Five Al-i-phats kick off our show
    Glycine, Alanine, Valine and then
    Leucine and Iso make up half of ten

    Well the next thing you know are three aromats
    phenylalanine(F) is right off the bat
    tYrosine has alcohol next to its ring
    And tryptophan(W) has indole double ring thing.

    Sulfur in Cysteine; it loves to bond
    Sulfur Methionine is much more a snob
    Alcoholic Serine, well wouldn't you know,
    And Threonine's OH gives a warm glow.

    Acid-aspartic(D) and glutamic(E) are ionized
    With pK of 4, their protons are lysed,
    asparagine(N) and glutamine(Q) play a different role
    With amides they're neutral but they both have poles

    lysine(K) and aRginine are the basic kind,
    But Histidine's imidazole can't make up its mind,
    Proline, the last one, coming at the end
    It's imine, an oddball, proteins use to bend.
    Alap Christy
    life is an empty bowl

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    thank Alap

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