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Thread: Pharmacology Mnemonics

  1. #1
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    Default Cardiovascular medicine

    HMG-CoA reductase inhibitors (statins): side effects, contraindications, interactions
    HMG-CoA:
    · Side effects:
    Hepatotoxicity
    Myositis [aka rhabdomyolysis]
    · Contraindications:
    Girl during pregnancy/ Growing children
    · Interactions:
    Coumarin/ Cyclosporine




    Antiarrhythmics: class III members
    BIAS:
    Bretylium
    Ibutilide
    Amiodarone
    Sotalol


    Beta-blockers: main contraindications, cautions
    ABCDE:
    Asthma
    Block (heart block)
    COPD
    Diabetes mellitus
    Electrolyte (hyperkalemia)




    Clopidogrel: use
    CLOPIdogrel is a drug that prevents
    CLots, an Oral Platelet Inhibitor (OPI).




    Amiodarone: action, side effects
    6 P's:
    Prolongs action potential duration
    Photosensitivity
    Pigmentation of skin
    Peripheral neuropathy
    Pulmonary alveolitis and fibrosis
    Peripheral conversion of T4 to T3 is inhibited -> hypothyroidism



    Beta blockers: members
    "The NEPAL Prime Minister":
    Timolol
    Nadolol
    Esmolol
    Pindolol
    Atenolol
    Labetalol
    Propranolol
    Metoprolol



    Ca++ channel blockers: uses
    CA++ MASH:
    Cerebral vasospasm/ CHF
    Angina
    Migranes
    Atrial flutter, fibrillation
    Supraventricular tachycardia
    Hypertension
    · Alternatively: "CHASM":
    Cererbral vasospasm / CHF
    Hypertension
    Angina
    Suprventricular tachyarrhythmia
    Migranes



    Beta-blockers: nonselective beta-blockers
    "Tim Pinches His Nasal Problem" (because he has a runny nose...):
    Timolol
    Pindolol
    Hismolol
    Naldolol
    Propranolol





    Antiarrhythmics: classification I to IV
    MBA College· In order of class I to IV:
    Membrane stabilizers (class I)
    Beta blockers
    Action potential widening agents
    Calcium channel blockers


    Enoxaprin (prototype low molecular weight heparin): action, monitoring
    EnoXaprin only acts on factor Xa.
    Monitor Xa concentration, rather than APTT

  2. #2
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    Thumbs up Pharmacology Mnemonics

    anti hyprtensive safe for pregnancy are---

    My N.H.L ---

    M-methyl dopa..
    N-nifedipine...
    H-hydralazine..
    L-labetalol.
    methyldopa
    M = mental retardation
    E = electrolyte imbalance
    T = tolerance
    H = headache/ hepatotoxicity, rebound HTN
    Y = psYchological upset
    D = dry mouth, drowsiness
    O = oedema, orthostatic hypotension
    P = Parkinsonism
    A = Anemia [+ve coomb's test]
    sodium nitroprusside

    clinical uses: MR. CHIEF SURGERY IN EMERGENCY

    Mr. = Acute MI
    chief = Acute CHF
    Surgery = maintain hemostasis during surgeries
    emergency = hypertensive emergencies
    antihypertensives used in emergencies.............
    Saurav Ganguly HELP
    S-sodium nitroprusside
    G-GTN
    H-hydralazine
    E-esmolol
    L-labetalol
    P-phentolamine
    Add All Mnemonics Related To Anti-Hypertensives Here By Replying To Post..


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  3. #3
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    Thumbs up Pharmacology Mnemonics

    All Mnemonics Are Really Catchy And Useful...
    If u Will Note Them Down Then 101% U Will Njoy Studying Pharmacology Atleast In This 2 Section..In Rest Sections Also I Have Posted Some Mnemonics e.g. in cvs..

    check them out and dont squeeze ur mind to mug up everything...



    Anticholinergic side effects

    "Know the ABCD'S of anticholinergic side effects":

    Anorexia
    Blurry vision
    Constipation/ Confusion
    Dry Mouth
    Sedation/ Stasis of urine
    Antimuscarinics: members, action

    "Inhibits Parasympathetic And Sweat":

    Ipratropium
    Pirenzepine
    Atropine
    Scopolamine
    _Muscarinic receptors at all parasympathetic endings sweat glands in sympathetic.
    Aspirin: side effects
    ASPIRIN:

    Asthma
    Salicyalism
    Peptic ulcer disease/ Phosphorylation-oxidation uncoupling/ PPH/ Platelet disaggregation/ Premature closure of PDA
    Intestinal blood loss
    Reye's syndrome
    Idiosyncracy
    Noise (tinnitus)
    Benzodiazapines: ones not metabolized by the liver (safe to use in liver failure)

    LOT:

    Lorazepam
    Oxazepam
    Temazepam
    Benzodiazepenes: antidote

    "Ben is off with the flu":
    Benzodiazepine effects off with Flumazenil.
    Benzodiazepenes: drugs which decrease their metabolism
    "I'm Overly Calm":
    Isoniazid
    Oral contraceptive pills
    Cimetidine
    _ These drugs increase calming effect of BZDs by retarding metabolism.
    Benzodiazepines: actions
    "Ben SCAMs Pam into seduction not by brain but by muscle":
    Sedation
    anti-Convulsant
    anti-Anxiety
    Muscle relaxant
    Not by brain: No antipsychotic activity.
    Beta selective blockers
    "BEAM ONE up, Scotty":
    Beta blockers:
    Esmolol
    Atenolol
    Metropolol

    Botulism toxin: action, related bungarotoxin

    Action: "Botulism Bottles up the Ach so it can't be the released":
    Related bungarotoxin: "Botulism is related to Beta Bungarotoxin (beta-, not alpha-bungarotoxin--alpha has different mechanism).

    Cholinergics (eg organophosphates): effects

    If you know these, you will be "LESS DUMB": or SLUDGE
    Lacrimation
    Excitation of nicotinic synapses
    Salivation
    Sweating
    Diarrhea
    Urination
    Micturition
    Bronchoconstriction

    Delerium-causing drugs

    ACUTE CHANGE IN MS:

    Antibiotics (biaxin, penicillin, ciprofloxacin)
    Cardiac drugs (digoxin, lidocaine)
    Urinary incontinence drugs (anticholinergics)
    Theophylline
    Ethanol
    Corticosteroids
    H blockers
    Antiparkinsonian drugs
    Narcotics (esp. mepridine)
    Geriatric psychiatric drugs
    ENT drugs
    Insomnia drugs
    NSAIDs (eg indomethacin, naproxin)
    Muscle relaxants
    Seizure medicines


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  4. #4
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    Default Here Is More

    Direct sympathomimetic catecholamines
    DINED:
    Dopamine
    Isoproterenol
    Norepinephrine
    Epinephrine
    Dobutamine
    Inhalation anesthetics
    SHINE:
    Sevoflurane
    Halothane
    Isoflurane
    Nitrous oxide
    Enflurane
    _ If want the defunct Methoxyflurane too, make it MoonSHINE.
    Ipratropium: action
    Atropine is buried in the middle: iprAtropium, so it behaves like Atropine.

    Lead poisoning: presentation
    ABCDEFG:
    Anemia
    Basophilic stripping
    Colicky pain
    Diarrhea
    Encephalopathy
    Foot drop
    Gum (lead line)
    Lithium: side effects
    LITH:
    Leukocytosis
    Insipidus [diabetes insipidus, tied to polyuria]
    Tremor/ Teratogenesis
    Hypothyroidism
    MAOIs: indications
    MAOI'S:
    Melancholic [classic name for atypical depression]
    Anxiety
    Obesity disorders [anorexia, bulemia]
    Imagined illnesses [hypochondria]
    Social phobias
    _ Listed in decreasing order of importance.
    _ Note MAOI is inside MelAnchOlIc.

    Methyldopa: side effects
    METHYLDOPA:
    Mental retardation
    Electrolyte imbalance
    Tolerance
    Headache/ Hepatotoxicity
    psYcological upset
    Lactation in female
    Dry mouth
    Oedema
    Parkinsonism
    Anaemia (haemolytic)
    Monoamine oxidase inhibitors: members
    "PIT of despair":
    Phenelzine
    Isocarboxazid
    Tranylcypromine
    _ A pit of despair, since MAOs treat depression.
    Morphine: effects
    MORPHINES:
    Miosis
    Orthostatic hypotension
    Respiratory depression
    Pain supression
    Histamine release/ Hormonal alterations
    Increased ICT
    Nausea
    Euphoria
    Sedation
    Morphine: effects at mu receptor
    PEAR:
    Physical dependence
    Euphoria
    Analgesia
    Respiratory depression
    Narcotic antagonists
    The Narcotic Antagonists are NAloxone and NAltrexone.
    _ Important clinically to treat narcotic overdose.
    Parkinsonism: drugs
    SALAD:
    Selegiline
    Anticholinenergics (trihexyphenidyl, benzhexol, ophenadrine)
    L-Dopa + peripheral decarboxylase inhibitor (carbidopa, benserazide)
    Amantadine
    Dopamine postsynaptic receptor agonists (bromocriptine, lisuride, pergolide)

  5. #5
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    Default Njoy..

    Phenytoin: adverse effects
    PHENYTOIN:
    P- interactions
    Hirsutism
    Enlarged gums
    Nystagmus
    Yellow-browning of skin
    Teratogenicity
    Osteomalacia
    Interference with B metabolism (hence anemia)
    Neuropathies: vertigo, ataxia, headache
    Physostigmine vs. neostigmine
    LMNOP:
    Lipid soluble
    Miotic
    Natural
    Orally absorbed well
    Physostigmine
    _ Neostigmine, on the contrary, is:
    Water soluble
    Used in myesthenia gravis
    Synthetic
    Poor oral absorption
    Pupils in overdose: morphine vs. amphetamine
    "MorPHINE: Fine. AmPHETamine: Fat":
    Morphine overdose: pupils constricted (fine).
    Amphetamine overdose: pupils dilated (fat).
    Serotonin syndrome: components
    Causes HARM:
    Hyperthermia
    Autonomic instability (delirium)
    Rigidity
    Myoclonus
    Sodium valproate: side effects
    VALPROATE:
    Vomiting
    Alopecia
    Liver toxicity
    Pancreatitis/ Pancytopenia
    Retention of fats (weight gain)
    Oedema (peripheral oedema)
    Appetite increase
    Tremor
    Enzyme inducer (liver)
    Succinylcholine: action, use
    Succinylcholine gets Stuck to Ach receptor, then Sucks ions in through open pore.
    You Suck stuff in through a mouth-tube, and drug is used for intubation.
    Tricyclic antidepressants: members worth knowing
    "I have to hide, the CIA is after me":
    Clomipramine
    Imipramine
    Amitrptyline
    _ If want the next worth knowing, the DNDis also after me:
    Desipramine
    Norrtriptyline
    Doxepin
    Tricyclic antidipressents (TCA): side effects TCA'S:
    ThrombocytopeniaCardiac (arrhymia, MI, stroke)
    Anticholinergic (tachycardia, urinary retention, etc)
    Seizures
    Vigabatrin: mechanism
    Vi-GABA-Tr-In:
    Via GABA Transferase Inhibition
    Antibiotics contraindicated during pregnancy
    MCAT:
    Metronidazole
    Chloramphenicol
    Aminoglycoside
    Tetracycline
    Busulfan: features
    ABCDEF:
    Alkylating agent
    Bone marrow suppression s/e
    CML indication
    Dark skin (hyperpigmentation) s/e
    Endrocrine insufficiency (adrenal) s/e
    Fibrosis (pulmonary) s/e
    Metabolism enzyme inducers
    "Randy's Black Car Goes Putt Putt and Smokes":
    Rifampin
    Barbiturates
    Carbamazepine
    Grisoefulvin
    Phenytoin
    Phenobarb
    Smoking cigarettes

  6. #6
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    Default More Added

    Morphine: side-effects
    MORPHINE:
    Myosis
    Out of it (sedation)
    Respiratory depression
    Pneumonia (aspiration)
    Hypotension
    Infrequency (constipation, urinary retention)
    Nausea
    Emesis
    Therapeutic index: formula
    TILE:
    Code:
    TI = LD / ED
    Zero order kinetics drugs (most common ones)
    "PEAZ (sounds like pees) out a constant amount":
    Phenytoin
    Ethanol
    Aspirin
    Zero order
    _ Someone that pees out a constant amount describes zero order kinetics (always the same amount out)
    Asthma drugs: leukotriene inhibitor action
    zAfirlukast: Antagonist of lipoxygenase
    zIlueton: Inhibitor of LT receptor
    Beta- vs Beta- receptor location
    "You have heart and lungs":
    Beta- are therefore primarily on heart.
    Beta- primarily on lungs.
    Hepatic necrosis: drugs causing focal to massive necrosis
    "Very Angry Hepatocytes":
    Valproic acid
    Acetaminophen
    Halothane
    Adrenoceptors: vasomotor function of alpha vs. beta
    ABCD:
    Alpha = Constrict.
    Beta = Dilate.

    Beta blockers with intrinsic sympathomimetic activity
    Picture diabetic and asthmatic kids riding away on a cart that rolls on pinwheels.
    Pindolol and Carteolol have high and moderate ISA respectively, making them acceptable for use in some
    diabetics or asthmatics despite the fact that they are non-seletive beta blockers.
    Beta-blockers: main contraindications, cautions
    ABCDE:
    Asthma
    Block (heart block)
    COPD
    Diabetes mellitus
    Electrolyte (hyperkalemia)
    Beta-blockers: nonselective beta-blockers "Tim Pinches His Nasal Problem" (because he has a runny nose...):
    Timolol
    Pindolol
    Hismolol
    Naldolol
    Propranolol

  7. #7
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    Cool Pharmacology Mnemonics

    (1)PREANASTHETIC MEDICATION

    HOSANA this is a christian word.
    H-H2blockers
    O-opeoids
    S-sedatives-antianxiety
    A-anticholenergic
    N-neuroleptics
    A-antiemetics
    simple and sobar

    (2)anti epeleptic drugs

    Dr.BHAISAB's New PC.

    D...deoxy barbiturates
    B...barbiturates
    H....hydantoin
    A.. aliphatic carb acids
    I....iminostilbenes
    S....succinimides
    B....BZD's
    N.... newer drugs
    P....Phenyltriazines
    C... cyclic gaba analogues
    (3)adverse effects of tetracyclins-KAPIL DEV
    K kidney toxicity
    A antianabolic effect
    P phototoxicity
    I inc ICP
    L liver toxicity

    D diabetes insipidus
    E enamel problems
    V vestibular toxicity
    (4)GENERAL TOXICITY OF ANTICANCER DRUGS
    SHaLi's BF Ghoghari Gautam is Chor.
    S-skin
    H-hyperurecemia
    L-lymphoreticular tissue
    B-bone marrow
    F-Foetus
    G-gonads
    G-git
    C-carcinogenecity
    (5)6 H s and 8 H s of adverse effects of thaizide diuretics and loop diuretics respectively.....

    (6)'melbourne cricket authority has high funds though players get minor amount' .. for clinical uses of beta blockers...
    (7)Drugs causing pulmonary fibrosis:

    BAB like in baba (father)
    Bleomycin
    Amiodarone
    Busulfan
    (8)ADRS OF CHLORAMPHENICOL

    smart boys in girls hostel
    B.... bone marrow depression
    H...hypersensitivity
    I....irritative effects
    S.....superinfections
    G.....Gray baby syndrome

    (9)ampicillin uses

    UR GMCS BeST
    UTI
    Respi
    Gonorrhoea
    Maningitis
    cholecystitis
    septicemias
    bacillary dysentry
    sabe
    typhoid
    (10)misch
    Acyclovir “I see clover”

    I see a three-leaf clover (this is a prodrug that gets converted into a triphosphate – it resembles dNTP and inhibits DNA Polymerase). Imagine putting clovers over herpes sores and genital warts (this is used to treat those).

    Amantadine “Homan to Dean” In case you haven’t heard, Dr. Homan is our new SOM dean. His new policy: he won’t let us come to school without our white coats (this drug blocks uncoating, stage 2, in viral infection). Other interesting facts about him: he can pee for 12 hours straight! (The half-life is 12h and it’s excreted unchanged in the kidney .)
    Dr. Homan can’t take the pressure of being a new dean so he becomes a nervous drunk with depression, feelings of detachment, insomnia, dizziness, ataxia, slurred speech, and inability to concentrate (these are some of the adverse effects)

    Cephachlor “Chlorine” – as in swimming pools
    You swim and get water up your nose and in your ears (this drug treats sinusitis and OTITIS media).

    Cephadroxil “Drop rocks” While you are peeing you drop rocks (This drug treats UTIs).

    Cephalothin “…Loathing”
    If your heart is infected, you can’t love, only loathe (this is used to treat severe infections such as endocarditis).

    Cephamandole “…Man doll” You have to inflate your man doll and you get an upper respiratory infection. If you “use” this anatomically correct man doll, he will give you pelvic inflammatory disease (This drug is indicated for URI and PID). He’s also so real that he bleeds!!! (Adverse effect: It affects Vit-K dependent clotting function)

    Cephazolin “…Soul in” You want to keep your soul in and not die if you go to surgery (this drug is used prophylactically for surgery).

    Cephoperazone “…Opera zone” Going to the opera makes me want to get drunk to the point of illness. These drugs, when mixed with ethanol interfere with ALDH, affecting alcohol metabolism (you end up with increased acetaldehyde – a DISULFIRAM-LIKE REACTION).
    Also, if you see Phantom of the Opera, expect to see some blood! (This affects Vit-K dependent clotting function.)

    Cephotaxime “…Tax time” IRS is hard to kill off – they are MULTIPLE DRUG RESISTANT (Use this drug against MDR strains.).

    Clindamycin “Clean the mice”
    You’re cleaning the mice because they are covered with ticks (this drug is used to treat Lyme Disease). You have to use SOS kitchen cleaner to clean the mice (SOS = 50 S ribosomal unit – where this drug acts).
    Richard Gere likes to put mice in “where the sun don’t shine” and this is a very FRAGILE procedure (Clindamycin may cause Pseudomembranous enterocolitis and it’s also used to treat B. fragilis infections).

    Fluconazole “Flu cone” Imagine an emaciated AIDS patient eating an ice cream cone made of the flu and he gets an oral and esophageal fungal infection. (This is used to treat oral and esophageal candidiasis in AIDS patients).

    Foscarnet “Fox cARRR net” If you catch foxes in a net, they won’t reproduce (this drug is a stage 3 inhibitor). ARRR… it inhibits RNA polymerase and Reverse transcriptase to block Reproduction. You’re going to put the foxes into a car that’s made out of bones instead of metal (this drug binds to bones and decreases Ca2+ and Mg2+).
    Also, a foxy lady is HOT (this drug will cause a fever) and never wear fox urine to hunt (this is excreted in the kidney and causes renal insufficiency).

    (11)inhalational corticosteroids

    Bed Bug Flew To Florida
    B-BECLOMETHASONE DIPROPIONATE
    B-BUDESONIDE
    F-FLUTICASONE PROPIONATE
    T-TRIAMCINALONE
    F-FLUNISOLIDE
    Alap Christy
    life is an empty bowl

  8. #8
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    Cool

    1.Succinylcholine: action, use

    Succinylcholine gets Stuck to Ach receptor, then Sucks ions in through open pore.
    You Suck stuff in through a mouth-tube, and drug is used for intubation
    2.Cholinergics (eg organophosphates): effects
    If you know these, you will be "LESS DUMB":
    Lacrimation
    Excitation of nicotinic synapses
    Salivation
    Sweating
    Diarrhea
    Urination
    Micturition
    Bronchoconstriction
    3.Steroids: side effects
    BECLOMETHASONE:
    Buffalo hump
    Easy bruising
    Cataracts
    Larger appetite
    Obesity
    Moonface
    Euphoria
    Thin arms & legs
    Hypertension/ Hyperglycaemia
    Avascular necrosis of femoral head
    Skin thinning
    Osteoporosis
    Negative nitrogen balance
    Emotional liability
    4.Methyldopa: side effects
    METHYLDOPA:
    Mental retardation
    Electrolyte imbalance
    Tolerance
    Headache/ Hepatotoxicity
    psYcological upset
    Lactation in female
    Dry mouth
    Oedema
    Parkinsonism
    Anaemia (haemolytic)
    5.Sodium valproate: side effects
    VALPROATE:
    Vomiting
    Alopecia
    Liver toxicity
    Pancreatitis/ Pancytopenia
    Retention of fats (weight gain)
    Oedema (peripheral oedema)
    Appetite increase
    Tremor
    Enzyme inducer (liver)
    6.
    Captopril (an ACE inhibitor): side effects
    CAPTOPRIL:
    Cough
    Angioedema/ Agranulocystosis
    Proteinuria/ Potassium excess
    Taste changes
    Orthostatic hypotension
    Pregnancy contraindication/ Pancreatitis/ Pressure drop (first dose hypertension)
    Renal failure (and renal artery stenosis contraindication)/ Rash
    Indomethacin inhibition
    Leukopenia/ Liver toxicity
    7.Lithium: side effects
    LITH:
    Leukocytosis
    Insipidus [diabetes insipidus, tied to polyuria]
    Tremor/ Teratogenesis
    Hypothyroidism
    8.Opioids: effects
    BAD AMERICANS:
    Bradycardia & hypotension
    Anorexia
    Diminished pupilary size
    Analgesics
    Miosis
    Euphoria
    Respiratory depression
    Increased smooth muscle activity (biliary tract constriction)
    Constipation
    Ameliorate cough reflex
    Nausea and vomiting
    Sedations

    9.Ca++ channel blockers: uses
    CA++ MASH:
    Cerebral vasospasm/ CHF
    Angina
    Migranes
    Atrial flutter, fibrillation
    Supraventricular tachycardia
    Hypertension
    ·
    Alternatively: "CHASM":
    Cererbral vasospasm / CHF
    Hypertension
    Angina
    Suprventricular tachyarrhythmia
    Migranes
    Alap Christy
    life is an empty bowl

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    Lightbulb Nervous System Pnemonics

    Pupils in overdose: morphine vs. amphetamine
    MorPHINE: Fine.
    AmPHETamine: Fat
    "Morphine overdose: pupils constricted (fine)
    Amphetamine overdose: pupils dilated (fat)

    Phenobarbitone side effects
    Children are annoying (hyperkinesia, irritability, insomnia, aggression)
    Adults are dosy (sedation, dizziness, drowsiness


    Atropine: origin tells action or vice versa
    Atropine causes your pupils to dilate, and it came from nightshade [belladona]In the night or in shade, your pupils dilate so you can see

    Atropine use: tachycardia or bradycardia
    "A goes with B":Atropine used clinically to treat Bradycardia


    Reserpine action
    Reserpine depletes the Reserves of catecholamines [and serotonin]

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    Default

    thank you for this pharmocology pmneumonics.......its very useful and made easy to remember

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