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Thread: Pharmacological classification of drugs

  1. #21
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    Antiplatelets Or antithrombotics


    Aspirin and other nsaids
    dipyridamole
    ticlopidine
    clopidogrel
    GP IIb/IIIa antagonist
    abciximab
    tirofiban



  2. #22
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    B-Blockers


    Nonselective
    a. Without intrinsic sympathomimetic activity- propranolol, sotalol, timolol
    b. With intrinsic sympathomimetic activity- pindolol
    c. With additional alpha blocking poperty- labetalol, carvedilol

    cardioselective
    metoprolol, atenolol, acebutolol, bisoprolol, esmolol, betaxolol, celiprolol.

    Selective beta2
    butoxamine, ICI 118551

  3. #23
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    Drugs For Bronchial Asthama


    |] brochodilators
    (A) sympathomimetics- adrenaline, isoprenaline, salbutamol, formoterol, salmeterol, terbutaline, bambuterol.
    (B) methylxanthines-
    theophylline(anhydrous), aminophylline, choline theophyllinate, hydroxyethyl theophylline, theophylline ethanolate or piperazine.
    (C) anticholinergics-
    atropine methonitrate, ipratropium bromide, tiatropium bromide.

    II] leukotriene antagonists
    montelukast, zafirlukast

    III] mast cell stabilizers
    sodium chromoglycate, nedocromil, ketotifen

    iv] corticosteroids
    (a) systemic- hydrocortisone, prednisolone & others
    (b) inhalational- beclomethasone dipropionate, budesonide, fluticasone propionate, flunisolide.







  4. #24
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    Drugs for Carcinoma of breast


    A. Non invasive (in situ) carcinoma
    1. Intratductal carcinoma
    2. Lobular carcinoma in situ

    B. Invasive carcinoma
    1. Infiltrating (invasive) duct carcinoma- NOS (not otherwise specified)
    2 Infiltrating (invasive) lobular carcinoma
    3. Medullary carcinoma
    4. Colloid (mucinou) carcinoma
    5. Papillary carcinoma
    6. Tubular carcinoma
    7. Adenoid cystic (invasive cribriform) carcinoma
    8. Secretory (juvenile) carcinoma
    9. Inflammatory carcinoma
    10. Carcinoma with metaplasia

    C. Paget's disease of the nipple










  5. #25
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    Cephalosporins


    First generation
    parenteral oral
    cephalothin cephalexin
    cefazolin cephradine
    cefadroxil

    second generation
    parenteral oral
    cefuroxime cefaclor
    cefoxitin cefuroxime axetil

    third generation
    parenteral oral
    cefotaxime cefixime
    ceftizoxime cefpodoxime proxetil
    ceftriaxone cefdinir
    ceftazidime ceftibuten
    cefoperazone

    fourth generation
    parenteral
    cefepime
    cefpirome







  6. #26
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    Chelating Agents


    Dimercaprol (BAL)
    dimercaptosuccinic acid
    calcium disodium edetate
    calcium disodium DPTA
    disodium edetate
    desferrioxamine
    deferiprone
    d penicillamine





  7. #27
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    Corticosteroids



    Glucocorticoids
    1. Short acting (biological t 1/2 <12 hrs)
    hydrocortisone (cortisol)
    cortisone
    2. Intermediate acting (12 - 36 hrs)
    prednisolone
    methylprednisolone
    triamcinolone
    3. Long acting ( >36 hrs)
    paramethasone
    dexamethasone
    betamethasone


    mineralocorticoids
    desoxycorticosterone acetate (DOCA)
    fludrocortisone
    aldosterone







  8. #28
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    Diuretics



    1. High efficacy diuretics (inhibitors of na+ k+ 2cl- cotransport)
    (a) sulphamoyl derivatives- furosemide, bumetanide
    (b) phenoxyacetic acid derivative- ethacrynic acid
    (c) organomercurials- mersalyl

    2. Medium efficacy diuretics (inhibitors of na+ cl- symport)
    (a) benzothiadiazines (thiazides)-
    chlorothiazide, hydrochlorothiazide, benzthiazide, hydroflumethiazide, clopamide
    (b) thiazide like-
    chlorthalidone, metolazone, xipamide, indapamide.

    3. Weak or adjunctive diuretics
    (a) carbonic anhydrase inhibitors- acetazolamide.
    (b) potassium sparing diuretics-
    . Aldosterone antagonist
    spironolactone
    . Directly acting (inhibitors of renal epithelial na+ channels)
    triamterene, amiloride.
    (c) osmotic diuretics
    mannitol, isosorbide, glycerol.
    (d) xanthines- theophylline.










  9. #29
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    Drugs for Constipation


    Laxatives
    (aperients, purgatives, cathartics)
    1. Bulk forming
    dietary fibre: bran, psyllium (plantago)
    ispaghula, methylcellulose, agar agar
    2. Stool softner (emolients)
    docusates (DOSS), liquid paraffin
    3. Stimulant purgatives
    (a) diphenylmethanes - phenolphthalein, bisacodyl
    (b) anthraquinones (emodins)
    senna, cascara sagrada
    (c) fixed oil
    castor oil
    4. Osmotic purgatives
    Mg salts - sulfate, hydroxide
    na salts - sulfate, phosphate
    sod.pot.tartarate
    lactulose
    5. Newer prokinetics
    5 HT3 antagonist alosterone
    5 HT4 antagonist tegesterone








  10. #30
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    Fibrinolytics (thrombolytics)


    Streptokinase
    urokinase
    alteplase




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