Thread: drugs acting on the eye

(pharmacology)
1. Direct-acting cholinergic
agonists include:
a. pilocarpine
b. echothiophate
iodide
c. carbachol
d. tropicamide
e. atropine
2. The ocular effects of
prostaglandins include:
a. breakdown of
blood-aqueous barrier
b. miosis
c. conjunctival
hyperaemia
d. eyelid retraction
e. ocular hypertension
3. True statements about
carbonic anhydrase
inhibitors include:
a. at least 50% of the
carbonic anhydrase
needs to be inhibited
before the
intraocular pressure
shows a significant
drop
b. they inhibits
carbonic anhydrase
found in the non-
pigmentary ciliary
epithelium.
c. shallowing of the
anterior chamber is a
feature
d. transient
hypermetropia is a
feature
e. it can cause
thinning of the cornea
if given topically
4. The effect of pilocarpine
include:
a. increased incidence
of retinal tear
b. increased tension in
the zonules
c. contraction of the
ciliary body
d. increased thickness
of the lens
e. increased
permeability of the iris
vessels
5. Phenylephrine:
a. directly stimulates
the alpha-adrenergic
receptors
b. affects the
accommodation
c. stops the pupil
response to bright
light
d. causes mydriasis
which does not
respond to pilocarpine
e. causes rebound
miosis
6.The following are true about
physostigmine:
a. it is a reversible
cholinesterase
b. it does not penetrate the
blood-brain barrier
c. it acts on the muscarinic
receptors
d. it acts on the nicotinic
receptors
e. it causes miosis
7.Physostigmine:
a. causes accommodative
spasm
b. causes conjunctival
vasoconstriction
c. increases the intraocular
pressure
d. causes twitching of the
eyelids
e. can be used in infestation
caused by pubic lice
8 Pilocarpine:
a. is an alkaloid derived
from plant
b. is a direct acting
muscarinic agonist
c. causes contraction of the
longitudinal muscles of the
ciliary
body
d. worsens myopia
e. has a greater effect on
patients with blue iris than
brown iris.
9 Cocaine:
a. decreases conduction of
nerve impulses
b. has an anaesthetic effect
on the cornea
c. is a direct stimulator of
the adrenergic receptors
d. causes tachycardia
e. causes increased blood
pressure
.10. Mydriasis occurs with:
a. thymoxamine
b. guanethidine
c. carbachol
d. neostigmine
e. ecothiophate

(Code)1.ac true
2.abce true
3.bc true
4.acde true
5.ade true
6.acde true
7.ade true
8.all true
9.abde
10.ab true(/code)