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Thread: Lange Endocrine Physiology Self-Assessment Questions

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    Lange Endocrine Physiology Self-Assessment Questions


    Which of the following statements concerning a particular hormone (hormone X) is correct?

    A. It will bind to cell membrane receptors in all cell types.
    B. It is lipid soluble and has an intracellular receptor.
    C. It circulates bound to a protein, and this shortens its half-life.
    D. It is a small peptide; therefore, its receptor localization will be in the nucleus.



    Answer / Explanation:

    [HIDE]
    The answer is B.

    B. It is lipid soluble and has an intracellular receptor.[/
    [/HIDE]
    .

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    Which of the following would be expected to alter hormone levels?



    A. Changes in mineral and nutrient plasma levels
    B. Pituitary tumor
    C. Transatlantic flight
    D. Training for the Olympics
    E. All of the above


    -----------
    Answer / Explanation:

    [HIDE]
    The answer is E.
    E. All of the above
    [/HIDE]

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    Which of the following statements concerning hormonal regulation is correct?



    A. A hormone does not inhibit its own release.
    B. The substrate a hormone regulates does not affect that hormone's release.
    C. Negative feedback regulation occurs only at the level of the anterior pituitary.
    D. Feedback inhibition may be exerted by nutrients and hormones.


    -----------
    Answer / Explanation:

    [HIDE]
    The answer is D.
    D. Feedback inhibition may be exerted by nutrients and hormones.

    [/HIDE]

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    The structure of a newly discovered hormone shows that it is a large peptide with a glycosylated subunit. The hormone is likely to:


    A. Bind to DNA and affect gene transcription
    B. Bind to adenylate cyclase and stimulate protein kinase C
    C. Bind to a cell membrane receptor
    D. Be secreted intact in the urine


    -----------
    Answer / Explanation:

    [HIDE]
    The answer is C.
    Bind to a cell membrane receptor

    [/HIDE]

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    The renal effects of arginine vasopressin (ADH) are mediated by:


    A. Binding to V2 G protein–coupled receptor, protein phosphorylation, and insertion of aquaporin 2 into luminal cell membrane in collecting duct

    B. Binding to nuclear receptors, protein phosphorylation, and insertion of aquaporin 2 into basolateral membrane of collecting duct

    C. Binding to V1 G protein–coupled receptor, protein phosphorylation, and insertion of aquaporin 1 into luminal cell membrane of collecting duct

    D. Binding to nuclear receptors, protein phosphorylation, and insertion of aquaporin 2 into luminal cell membrane of collecting duct


    -----------
    Answer / Explanation:

    [HIDE]
    The answer is A.

    A. Binding to V2 G protein–coupled receptor, protein phosphorylation, and insertion of aquaporin 2 into luminal cell membrane in collecting duct


    [/HIDE]

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    On a hot summer day, the release of ADH occurs:

    A. When plasma osmolality is 270 mOsm/kg
    B. Immediately following stimulation of thirst
    C. Before an 8% decrease in blood volume
    D. Before stimulation of thirst


    -----------
    Answer / Explanation:

    [HIDE]
    The answer is D.

    D. Before stimulation of thirst

    [/HIDE]

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