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Thread: Pharma quiz #1

  1. #1
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    Talking Pharma quiz #1

    Pharma quiz #1



    1. I.V route used n titration.
    2. oral routes r commonly used 4 chronic administeration.
    3. Intrathecal route 4 drugs to pass to CNS.
    4. Oraly routes r unsutable 4 unconscious pt.
    5. Intraarterial is commonly used 4 dranage to specific organ.
    6. I.M 4 injecting procine penicillin.
    7. Rectal partially by pass portal circulation.
    8. I.V 100% bioavalibility.


    1. filtration is affected (decreased) by heart falier.(T)
    2. drug which r bounded to plasmaproteins cannot be excreted by tubular sec.(F).
    3. bounded drug is inactive(T).
    4. degree of bounded drug increases n liver dis.(F)
    5. alcohol present n milk by passive diffusion due to hydrophilic ionization(F).
    6. diazepam found n plasma(F).
    7. vasopresin can be used n transdermal patches to prevent it digestion n GIT(F).
    8. gas & salbutamal r the only ways to be administerated by pulmonary routes(F).
    9. protein bound drugs can be actively transported across the cell memb.(T).
    10. gentamicin can be distributed n total body water due to polar solubility(F).
    11. penicillin can penetrate brain n high conc. n meningitis(T).
    12. redistribution is termination of thiopentone(T).

    1. L –dopa is actively transport.
    2. P-glycoprotein is used n efflex transport protein.
    3. rifampin r e.g.of enterohepatic circulation.
    4. facilitated diffusion along conc. Gradient.
    5. penicillin sec. Is inhibited by probencid.
    6. ledocin is an anesthetic prolonged its action by injection of vasoconstrictor (epinephrine).
    7. Entericcoated tablets prevent irritation of gastric mucosa.
    8. nitroglycerine can be administerated by sublingual routes.
    9. chloroquine deposit n melanin pig. n eye.
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  2. #2
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    Arrow Pharma quiz #2#

    Pharma quiz #2#
    1. N-acetyl transferase all r true except:
    Non microsomal enzyme phase-I.
    2. All r enzymes inhibitor or inducers except:
    Penecillin.
    3. A man weight 80 kg & his vd=4, cp=0.25 calculate LD?
    Ans=80
    4. If the half time=6 hr, what is the time needed to elemenate 87.5%
    Ans=18 hr.
    5. In 0-order kinetics all r true except:
    Logarithmic plot of plasma conc. versus time is linear.
    6. Large changes at high plasma conc. of creatinine has more series consequences than small changes in small plasma conc.(F).

    7.matching:
    Vd ---------< dose/cp.
    Cl ----------< k×vd.
    Ld----------< vd×cp/s×f.
    Md----------<cl ×cpss× t/s× f .

    8.Matching:
    allupurinol--------< xanthane oxidase.

    Billirubin---------< glucuronidation.

    Phenobarbiton-----< mixed microsomal oxidation.

    Lidocain-----------< amidases.

    9.Give 4 factors affecting the clearance?

    10.If the oral dose giving =400mg ,F=0.5 calculate the IV dose?
    Ans=400×O.5=200mg.

    11.what is the time needed to reach study state of drug dose=300mg given every 12 hr?
    ans=4×12=48 hr.

    12.Mention e.g. of:
    a. inactive--------< active drug.
    b. Less toxic--------<high toxic drug.

    13.what is phenocopying?
    It is due to genetic variation of biotransformation (metabolism) ,so it is changing from extensive metabolites (EM) to poor metabolites(PM) …..EM---------<PM.

    e.g.quinidine, SSRI it will inhibits CYP2D6 so this will cause changing from EM--------< PM.
    " VALUE HAS A VALUE ONLY IF ITS VALUE IS VALUED "
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    Thumbs up Pharmacology quiz #3

    Pharmacology quiz #3


    1. Which one is mis-match?
    a. Carrier reserpine.
    b. Receptor adrenalin.
    c. Enzyme allopurinol.
    d. Ion channel asprin.

    2. Which one produces acute tolerance?
    a. Morphine
    b. Phenobarbiton.
    c.tyramin.
    d. Alcohol.

    3. Which one of the following is physiologically antagonism?
    Histamine & adrenalin.


    4.high dose of phenobarbitone is an e.g. of type A drug rxn (T).

    5. Match:
    a. prpphyria ---------------------< barbiturate.
    b. hepatocellular necrosis ------< paracetamol.
    c. cholestatic jaundice.----------< Methyl testosterone.


    6. Match:
    a. Tolerance-------------< reduction n response 2 drug.
    b. Partial agonist--------< has sub maximal effect & affinity.
    c. Therapeutic index----< the median lethal dose that determine
    the safety of drug .



    7. Give 4 differences b/w typeA & typeB ?

    8. Give 2 drugs that have teratogenic effect.

    9. Give 2 drugs that affect old people & must be avoided.

    10. Give 2 e.g. of adverse drug rxn that have genetic effect.

    11. Mention 2 dis. related to receptors.

    12. In neonates:
    - chloramphenicol cause gray baby syndrom.
    - gentamicin cause renal toxicity.

    13. Defin:
    - Affinity:
    - Intrinsic activity:

    14. Rifampin causes inducing of hepatic microsomal enzymes & lead to pregnancy, while cimetidine causes inhibiting of microsomal enzymes & lead to toxicity.
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    Lightbulb Pharma. Quiz #4

    Pharma. Quiz #4

    1. ttt of glaucoma is:
    a. pilocarpine.
    b. both.
    c. ecothiophate.
    d. neither.
    2. w one has short drug action:
    a. D-tubocurarine.
    b.Mivacurium.
    c.Pancurium.
    d.Gallamin.
    3. All r caused by anticholenergic drug except:
    a. Blurred vision.
    b. Increase sweating.
    c. Increase intraocular pressure.
    d. Constipation.
    4. All r caused by cholenergic action except:
    a. Decrease lacrimation.
    b. Decrease IOP.
    c. Accommodation 4 near vision.
    5. w drug is not used n examine fundus of eye:
    a.tropicamide
    b. atropine.
    d. homatropine.
    e. Pilocarpine.
    6. ttt of peptic ulcer is by:
    - pireznepine.
    7. ttt of Parkinson’s dis. is by:
    - benzotropine.
    8. ttt of bronchial asthma is by:
    - Ipratropium.
    9. w drug that decreases IOP:
    -phyosostigmine.


    1. Parasympathetic has the upper hand n dull innervations (T).
    2. = originates from thoracolumbar (F).
    3. = neurotransmitters r dopamine (F).
    4. = causes mydriasis (F).
    5. M2 r n stomach (F).
    6. phyosostigmine cross BBB & cause CNS lesions (T).
    7. cholinergic drugs + evacuation of urinary bladder (T).
    8. The heart contain M3 (F).
    9. muscarinic drugs causes tachycardia (F).
    10. muscarinic agonist causes vasoconstrictor & hypertension (F).

    1. Mention 2 sites of release of Ach.
    -CNS. – all preganglionic.
    3. Mention 2 cholinergic drugs &what is used 4.
    -pilocarpine------< ttt of glaucoma.
    -neostigmin------< ttt of myasthenia gravis.
    4. Mention 2 ttts 4 insecticides toxicity.
    -atropine. –oximes.
    5. Mention 2 contraindications of cholinergic drugs.
    -hypotention. –bronchial asthma.
    6. Mention 2 reversible anticholinesterase drugs.
    -physostigmine. –neostigmine.
    " VALUE HAS A VALUE ONLY IF ITS VALUE IS VALUED "
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    Wink

    Pharma. Quiz #5

    1. Phenylphrine is selective alph1 receptor.
    2.Nor-adrenergic affect alph1 ,alpha2 , B1 & little on B2 .
    3.Nor-adrenergic causes bradycardia by + vagal reflex.
    4.Salbutamol is selective B used n bronchial asthma.
    5.Naphazoline used n nasal congestion.
    6.Methoxamine is non-selective B agonist.
    7.Amphetamine act on alpha , B & CNS.
    8.Ritodrine is B2 agonist used n ttt of premature labor.
    9.Dopamine used n shock & renal profusion.
    10.Isoproternol is B selective 4 heart block.

    1.Ephedrine used n the direct + of adrenergic receptor & release of NE(T).
    2.Phenylphrine cause meiosis (F).
    3.Caticolamin can cross BBB (F).
    4.Adrenaline nasal packs is used n nasal bleeding(epistaxis) (T).
    5.Phenylphrine used n fundus examination (T).
    6.salbutamol is non-selective B agonist (F).
    7.Hemovanillyl acid or VMA is a metabolize of adrenalin (T).
    8.Phenylphrine used n bronchial asthma (F).
    9.NE can cause myosis (T).

    1. Mention 2 adverse effect of E.
    2. Mention 2 drugs used n ttt of asthma.
    3. Mention 1 drug has prolonged action on local anesthesia.
    4. Mention the action & uses of dobutamine.
    5. mention the action of isoproternol on heart & bl. Vessels.
    " VALUE HAS A VALUE ONLY IF ITS VALUE IS VALUED "
    Never Let Student Die In Your Heart When It Dies You Want Remain A Doctor But You Will Be A Technician

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    Cool Pharma quiz # 6

    Pharma quiz # 6

    1. prazosin is a selective alph1 blocker e long half life.
    2. doxazosin is a selective alpha1 blocker e short acting.
    3. labetalol have both alpha ,B blockers.
    4. phenoxybenzamine have alpha1 blocker & small amount of alpha2 blocker used n ttt of pheochromocytoma.
    5. methyl dopa is a sympatholytic & produce active metabolites.
    6. Atenolol is hydrophilic & cardio selective B blocker.
    7. Ergotamine can be given n aura.
    8. Reserpine is adrenergic neuron blocker,can be used n schizophrenia & psychosis.
    9. Clonidine used as anti hypertension & ttt of opiate e drowal.
    10.Nadolol non selective B blocker, long acting.

    a. Mention 2 drugs 2 treat glaucoma & its action to decrease IOP.
    b. Mention 4 drugs n cardio selective B blocker.
    c. Mention 2 adverse actions of cardio selective B blocker that is less much occur n cardio selective.
    1. alpha- blocker do not cause orthostatic hypotension (F).
    2. Methyldopa is contraindicated n pregnancy (F).
    3. Propranolol is used n angina , hyperthyroidism & n hypertension (T).
    4.Hydrophilic B blocker less cause nightmares & depression (T).
    5. Sotalol is B blocker used as anti arrethmic (T)
    " VALUE HAS A VALUE ONLY IF ITS VALUE IS VALUED "
    Never Let Student Die In Your Heart When It Dies You Want Remain A Doctor But You Will Be A Technician

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    Cool Pharma quiz # 7

    Pharma quiz # 7

    1. Mention 2 histamine releasers & 2 inhibitors.
    2. 4 therapeutic uses of diphenhydramin.
    3. 3 different b/w 1st generation & 2nd generation.
    4. Give an e.g. of drug & its uses n:
    - 5HT1A.
    - 5HT1D.
    - 5HT4.
    - leukotrine inhibitor.
    5. Mention the uses of:
    - ondransetron.
    - ketanserin.
    6. Mention 2 increased transporters of carcinoid tumor & 4 symptoms & the drug that block all these symptoms.
    7. Mention 3 drugs that affect kallekrin- kinin sys & 2 uses of one of them.
    8. 2 uses of kinins.
    9. 4 uses of PG & its type & 4 side effects.

    10. Matching:
    1. Cyproheptadine---------- 5HT,H1 antagonist, increase apitite.
    2. LDS----------------------- hallucination.
    3. cinnorisine---------------- ttt vertigo.
    4. metaclopramide---------- 5HT4 agonist, prokinetic.
    5. methysergide------------ migran prophylaxis.
    6. lantenoprost------------- ttt glaucoma.
    7. alprotadil---------------- ttt erectile dysfunction.
    8. promethazine------------ H1 antagonist.
    " VALUE HAS A VALUE ONLY IF ITS VALUE IS VALUED "
    Never Let Student Die In Your Heart When It Dies You Want Remain A Doctor But You Will Be A Technician

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