Prophylactic, empirical, pre-emptive and targeted antifungal treatment

Prophylaxis
Risk factor +
Biomarker-
Clinical sign -
Mycology -

Pre-emptive

Risk factor +
Biomarker +
Clinical sign +/-
Mycology -

Empirical
Risk factor +
Biomarker -
Clinical sign +/-
Mycology -
Targeted
Risk factor +
Biomarker +/-
Clinical sign +
Mycology +
Reference:
IDSA clinical practice guidelines (Clin Infec Dis 2009; 48: 503)
Clin Infect Dis. 2016 Feb 15;62(4):e1-50. doi: 10.1093/cid/civ933. Epub 2015 Dec 16

Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.
Code:
http://www.cid.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=26679628
Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group

Code:
http://cid.oxfordjournals.org/content/46/12/1813.long
Diagnosis of invasive candidiasis in the ICU

Code:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224461/

Antifungals in the ICU
Code:
http://journals.lww.com/co-infectiousdiseases/pages/articleviewer.aspx?year=2008&issue=12000&article=00007&type=abstract
Download PDF:
Code:
https://www.mediafire.com/?07wolhqm29w8inz
Ostrosky-Zeichner Clinical prediction rule for ICU acquired candidemia

A bedside scoring system ("Candida score") for early antifungal treatment in nonneutropenic patients