A bedside scoring system ("Candida score") for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization.

Leon score is a prediction model for invasive candidiasis and is calculated as follows
Multifocal Candida species colonization : 1.112 (1)

Surgery on ICU admission :0.997 (1)

Severe sepsis : 2.038 (2)

Total parenteral nutrition : 0.908 (1)
Central venous catheters were not a significant risk factor for proven candidal infection in this study.

In a large cohort of nonneutropenic critically ill patients in whom Candida colonization was prospectively assessed, a "Candida score">2.5 accurately selected patients who would benefit from early antifungal treatment.

Reference : Leon C et al. Crit Care Med. 2009; 37: 1624-33