Case Study:

A healthy 19-year-old primigravida is in the 12th week of her pregnancy when she develops vaginal spotting of blood and mild cramping abdominal pain. The pregnancy up to that point has been uncomplicated. On physical examination she is afebrile. There is vaginal bleeding but no exudate. A spontaneous abortion occurs a day later.
Which of the following conditions is most likely to produce these findings?
A Placental insufficiency

B Chromosomal abnormality

C Congenital infection

D Toxemia of pregnancy

E Maternal drug use

Answer / Explanation:



Abnormalities such as trisomy 16 are found in many first trimester abortuses.