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Thread: Pathology for Clinicians

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    Default Pathology for Clinicians

    Pathology for Clinicians

    Soft Tissue Sarcomas - Cases

    Clinical Presentation

    Diagnosis



    Soft Tissue Sarcomas - Case 1

    Clinical Presentation

    16-year old adolescent male presents with diffuse abdominal pain and distension. Laparotomy evaluation discloses a large gray mass attached to the peritoneum. The mass measures 19 cm and is surrounded by multiple nodules, also attached to the peritoneum, ranging in diameter from 1 to 4.5 cm.

    Microscopic examination of the large mass shows clusters of small round blue cells with an increased mitotic activity surrounded by a prominent desmoplastic stroma (pictures 1 and 2).


    Soft Tissue Sarcomas - Case 2

    Clinical Presentation

    A 45-year-old man presented with 6-month history of a deep seated and painless soft-tissue mass. A magnetic resonance imaging was performed and showed a 10 cm mass with a signal intensity close to the muscle's sign on T1. The mass was completely excised and on the macroscopic examination, it was white, fleshy, well-circumscribed and measured approximately 10 cm in greatest dimension. The microscopic exam disclosed a fascicular proliferation of spindle-shaped cells with mild to moderate mitotic activity and few areas of necrosis (figures 1-4).
    Immunohistochemical studies revealed the following profile:


    and much more-->




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    Last edited by trimurtulu; 11-12-2008 at 07:50 PM.

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